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19 March 1987

AZT Approved as First Antiretroviral Drug for HIV/AIDS

Health

The US FDA approved zidovudine (AZT) for use against HIV/AIDS, making it the first antiretroviral drug available. The approval came just 25 months after AZT was first shown to be active against HIV — a record-breaking timeline. While a crucial breakthrough demonstrating HIV could be treated, AZT had significant side effects and limited efficacy when used alone, and was at the time the most expensive drug in history.

Impact & Significance

Proved that antiretroviral treatment was possible, opening the door to the combination therapies that would eventually transform HIV from a death sentence into a manageable condition.

Reference Record

Date
19 March 1987
Era
1970-1989
Sources
1

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